The fully automated DTU Screening Core platform is design to perform biochemical and cell-based assays in 96-, 384- and 1536-well plate format, with great flexibility in terms of possible read-outs, thanks to the Tecan Spark Cyto 600 multimode microplate reader with cell-imaging function.
Production of assay ready plates with the in-house compound collection of DK-OPENSCREEN will be part of the activities of the platform and this will be handled by the acoustic liquid dispenser ECHO 550.
What we offer:
- Assay development
- Assay adaptation and miniaturization in HTS format
- Pilot screening
- Full library screening
- Focused subset library screening
- Hit confirmation
- Potency determination
- Data analysis
- Compound toxicity in Cell viability assays
Key points:
- Assays in 96-, 384- and 1536-well format
- 50 000 compounds from the DK-OPENSCREEN library
- Hit identification and data analysis
- Assay readouts:
- Absorbance UV/Vis
- Fluorescence
- Fluorescence polarization
- Luminescence
- Alpha technology
- Imaging (Fluorescence, Bright field, Digital phase contrast)
For information about prices, availability and for questions about specific assays or assay set-up, please, contact us at dtuscore@dtu.dk